PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Kalanchoe laxiflora
WOX Family
Species TF ID Description
Kaladp0002s0011.1.pWOX family protein
Kaladp0005s0048.1.pWOX family protein
Kaladp0008s0293.1.pWOX family protein
Kaladp0016s0082.1.pWOX family protein
Kaladp0016s0082.2.pWOX family protein
Kaladp0029s0096.1.pWOX family protein
Kaladp0029s0097.1.pWOX family protein
Kaladp0039s0544.1.pWOX family protein
Kaladp0039s0544.2.pWOX family protein
Kaladp0040s0534.1.pWOX family protein
Kaladp0053s0383.1.pWOX family protein
Kaladp0067s0061.1.pWOX family protein
Kaladp0070s0016.1.pWOX family protein
Kaladp0070s0019.1.pWOX family protein
Kaladp0070s0083.1.pWOX family protein
Kaladp0070s0139.1.pWOX family protein
Kaladp0071s0249.1.pWOX family protein
Kaladp0071s0250.1.pWOX family protein
Kaladp0071s0271.1.pWOX family protein
Kaladp0089s0019.1.pWOX family protein
Kaladp0095s0813.1.pWOX family protein
Kaladp0395s0025.1.pWOX family protein
Kaladp0822s0027.1.pWOX family protein
Kaladp0912s0009.1.pWOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590