PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Gossypium arboreum
E2F/DP Family
Species TF ID Description
Cotton_A_00474_BGI-A2_v1.0E2F/DP family protein
Cotton_A_02626_BGI-A2_v1.0E2F/DP family protein
Cotton_A_02627_BGI-A2_v1.0E2F/DP family protein
Cotton_A_05549_BGI-A2_v1.0E2F/DP family protein
Cotton_A_09611_BGI-A2_v1.0E2F/DP family protein
Cotton_A_29266_BGI-A2_v1.0E2F/DP family protein
Cotton_A_29667_BGI-A2_v1.0E2F/DP family protein
Cotton_A_30259_BGI-A2_v1.0E2F/DP family protein
Cotton_A_37863_BGI-A2_v1.0E2F/DP family protein
Cotton_A_38746_BGI-A2_v1.0E2F/DP family protein
Cotton_A_39109_BGI-A2_v1.0E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710