PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Citrus sinensis
AP2 Family
Species TF ID Description
orange1.1g005737mAP2 family protein
orange1.1g009943mAP2 family protein
orange1.1g010002mAP2 family protein
orange1.1g010039mAP2 family protein
orange1.1g010040mAP2 family protein
orange1.1g010454mAP2 family protein
orange1.1g010763mAP2 family protein
orange1.1g011009mAP2 family protein
orange1.1g011312mAP2 family protein
orange1.1g011372mAP2 family protein
orange1.1g012583mAP2 family protein
orange1.1g012632mAP2 family protein
orange1.1g013009mAP2 family protein
orange1.1g014099mAP2 family protein
orange1.1g014204mAP2 family protein
orange1.1g016650mAP2 family protein
orange1.1g018292mAP2 family protein
orange1.1g018673mAP2 family protein
orange1.1g018990mAP2 family protein
orange1.1g019391mAP2 family protein
orange1.1g019609mAP2 family protein
orange1.1g020517mAP2 family protein
orange1.1g021606mAP2 family protein
orange1.1g022082mAP2 family protein
orange1.1g036423mAP2 family protein
orange1.1g038243mAP2 family protein
orange1.1g039174mAP2 family protein
orange1.1g041657mAP2 family protein
orange1.1g042319mAP2 family protein
orange1.1g043551mAP2 family protein
orange1.1g044480mAP2 family protein
orange1.1g044828mAP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102