PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Citrullus lanatus
TCP Family
Species TF ID Description
Cla001506TCP family protein
Cla002099TCP family protein
Cla002323TCP family protein
Cla002428TCP family protein
Cla006219TCP family protein
Cla006939TCP family protein
Cla007113TCP family protein
Cla008721TCP family protein
Cla009096TCP family protein
Cla009785TCP family protein
Cla010176TCP family protein
Cla010762TCP family protein
Cla013523TCP family protein
Cla016274TCP family protein
Cla016452TCP family protein
Cla018312TCP family protein
Cla018516TCP family protein
Cla018555TCP family protein
Cla018622TCP family protein
Cla018993TCP family protein
Cla019050TCP family protein
Cla019117TCP family protein
Cla019567TCP family protein
Cla020050TCP family protein
Cla020363TCP family protein
Cla022939TCP family protein
Cla023342TCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426