PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Brassica oleracea
WOX Family
Species TF ID Description
XP_013584233.1WOX family protein
XP_013584234.1WOX family protein
XP_013584398.1WOX family protein
XP_013585006.1WOX family protein
XP_013585030.1WOX family protein
XP_013587710.1WOX family protein
XP_013595483.1WOX family protein
XP_013597183.1WOX family protein
XP_013597192.1WOX family protein
XP_013601823.1WOX family protein
XP_013602644.1WOX family protein
XP_013605677.1WOX family protein
XP_013610179.1WOX family protein
XP_013610365.1WOX family protein
XP_013610643.1WOX family protein
XP_013610840.1WOX family protein
XP_013610841.1WOX family protein
XP_013615820.1WOX family protein
XP_013616822.1WOX family protein
XP_013619447.1WOX family protein
XP_013619448.1WOX family protein
XP_013619525.1WOX family protein
XP_013619706.1WOX family protein
XP_013619939.1WOX family protein
XP_013623608.1WOX family protein
XP_013623609.1WOX family protein
XP_013624814.1WOX family protein
XP_013627080.1WOX family protein
XP_013627081.1WOX family protein
XP_013627082.1WOX family protein
XP_013627198.1WOX family protein
XP_013627905.1WOX family protein
XP_013630260.1WOX family protein
XP_013630336.1WOX family protein
XP_013630409.1WOX family protein
XP_013635058.1WOX family protein
XP_013637309.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590