PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Amaranthus hypochondriacus
G2-like Family
Species TF ID Description
AHYPO_000118-RAG2-like family protein
AHYPO_000143-RAG2-like family protein
AHYPO_002014-RAG2-like family protein
AHYPO_003989-RAG2-like family protein
AHYPO_004266-RAG2-like family protein
AHYPO_005423-RAG2-like family protein
AHYPO_005572-RAG2-like family protein
AHYPO_006152-RAG2-like family protein
AHYPO_008141-RAG2-like family protein
AHYPO_008565-RAG2-like family protein
AHYPO_008679-RAG2-like family protein
AHYPO_008895-RAG2-like family protein
AHYPO_009070-RAG2-like family protein
AHYPO_009281-RAG2-like family protein
AHYPO_009300-RAG2-like family protein
AHYPO_009460-RAG2-like family protein
AHYPO_009963-RAG2-like family protein
AHYPO_011178-RAG2-like family protein
AHYPO_011454-RAG2-like family protein
AHYPO_011911-RAG2-like family protein
AHYPO_011912-RAG2-like family protein
AHYPO_011945-RAG2-like family protein
AHYPO_012243-RAG2-like family protein
AHYPO_012412-RAG2-like family protein
AHYPO_012413-RAG2-like family protein
AHYPO_013476-RAG2-like family protein
AHYPO_013721-RAG2-like family protein
AHYPO_014173-RAG2-like family protein
AHYPO_014422-RAG2-like family protein
AHYPO_014626-RAG2-like family protein
AHYPO_015098-RAG2-like family protein
AHYPO_015632-RAG2-like family protein
AHYPO_015842-RAG2-like family protein
AHYPO_016830-RAG2-like family protein
AHYPO_017005-RAG2-like family protein
AHYPO_017754-RAG2-like family protein
AHYPO_020806-RAG2-like family protein
AHYPO_020842-RAG2-like family protein
G2-like Family Introduction

The GLK proteins are members of the recently categorized GARP superfamily of transcription factors (Riechmann et al., 2000) defined by G2 in maize; the Arabidopsis RESPONSE REGULATOR-B (ARR-B) proteins (Imamura et al., 1999); and the PHOSPHATE STARVATION RESPONSE1 (PSR1) protein of Chlamydomonas (Wykoff et al., 1999). In the case of G2, three of the four defining features of most transcription factors have been verified experimentally in heterologous systems. G2 is nuclearlocalized (Hall et al., 1998), is able to transactivate reporter gene expression, and can both homo-dimerize and heterodimerize with ZmGLK1 (Rossini et al., 2001). DNA-binding activity of GLK proteins has yet to be demonstrated,however, the putative DNA-binding domain is highly conserved with domains in other GARP proteins such as ARR1 and ARR2 (Riechmann et al., 2000). Notably, ARR1 and ARR2 have been shown to bind DNA (Sakai et al.,2000), thus it is likely that GLK proteins act as transcriptional regulators of chloroplast development.

The GLK proteins are members of the GARP superfamily of transcription factors, and phylogenetic analysis demonstrates that the maize, rice and Arabidopsis GLK gene pairs comprise a distinct group within the GARP superfamily. Further phylogenetic analysis suggests that the gene pairs arose through separate duplication events in the monocot and dicot lineages. As in rice, AtGLK1 and AtGLK2 are expressed in partially overlapping domains in photosynthetic tissue. GLK genes therefore regulate chloroplast development in diverse plant species.

Fitter DW, Martin DJ, Copley MJ, Scotland RW, Langdale JA.
GLK gene pairs regulate chloroplast development in diverse plant species.
Plant J. 2002 Sep;31(6):713-27.
PMID: 12220263