PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Species | TF ID | Description |
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AT1G19350.1 | BES1 family protein | |
AT1G19350.3 | BES1 family protein | |
AT1G19350.4 | BES1 family protein | |
AT1G19350.5 | BES1 family protein | |
AT1G19350.6 | BES1 family protein | |
AT1G75080.1 | BES1 family protein | |
AT1G75080.2 | BES1 family protein | |
AT1G78700.1 | BES1/BZR1 homolog 4 | |
AT2G45880.1 | beta-amylase 7 | |
AT3G50750.1 | BES1/BZR1 homolog 1 | |
AT4G18890.1 | BES1/BZR1 homolog 3 | |
AT4G36780.1 | BES1/BZR1 homolog 2 | |
AT5G45300.1 | beta-amylase 2 | |
AT5G45300.2 | beta-amylase 2 |
Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.
Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330